/* ============================================================
   VARIABLES & RESET
   ============================================================ */
:root {
  --pink:        #FF2D78;
  --pink-light:  #FF6FA8;
  --pink-pale:   #FFE4EF;
  --pink-deep:   #C4005A;
  --cream:       #F4EDE3;
  --cream-2:     #EBE1D5;
  --cream-stroke:#C0B0A0;
  --dark:        #0D0D0D;
  --dark-2:      #161616;
  --dark-3:      #1E1E1E;
  --light:       #F9F4F6;
  --white:       #FFFFFF;
  --text-muted:  #888;
  --border:      rgba(255,255,255,0.08);

  --font-body:   'Inter', sans-serif;
  --font-display:'Playfair Display', serif;

  --radius:      16px;
  --radius-lg:   28px;
  --transition:  0.35s cubic-bezier(0.4,0,0.2,1);
}

*, *::before, *::after { box-sizing: border-box; margin: 0; padding: 0; }

html { scroll-behavior: smooth; }

body {
  font-family: var(--font-body);
  background: var(--dark);
  color: var(--white);
  line-height: 1.7;
  overflow-x: hidden;
}

a { color: inherit; text-decoration: none; }
ul { list-style: none; }
img { max-width: 100%; }

/* ============================================================
   TYPOGRAPHY HELPERS
   ============================================================ */
.accent { color: var(--pink); }

/* ============================================================
   NAV
   ============================================================ */
.nav {
  position: fixed;
  top: 0; left: 0; right: 0;
  z-index: 100;
  display: flex;
  align-items: center;
  justify-content: space-between;
  padding: 1.25rem 3rem;
  background: rgba(13,13,13,0.7);
  backdrop-filter: blur(18px);
  -webkit-backdrop-filter: blur(18px);
  border-bottom: 1px solid var(--border);
  transition: background var(--transition);
}

.nav__logo {
  font-family: var(--font-display);
  font-size: 1.6rem;
  font-weight: 700;
  letter-spacing: -0.04em;
}

.nav__links {
  display: flex;
  gap: 2.5rem;
}

.nav__links a {
  font-size: 0.85rem;
  font-weight: 500;
  letter-spacing: 0.06em;
  text-transform: uppercase;
  color: var(--text-muted);
  transition: color var(--transition);
}

.nav__links a:hover { color: var(--pink); }

/* ============================================================
   HERO
   ============================================================ */
.hero {
  position: relative;
  min-height: 100vh;
  display: flex;
  flex-direction: column;
  justify-content: center;
  align-items: flex-start;
  padding: 10rem 3rem 5rem;
  overflow: hidden;
  background: var(--dark);
}

.hero::before {
  content: '';
  position: absolute;
  inset: 0;
  background:
    radial-gradient(ellipse 80% 60% at 60% 30%, rgba(255,45,120,0.22) 0%, transparent 70%),
    radial-gradient(ellipse 50% 40% at 10% 80%, rgba(255,45,120,0.10) 0%, transparent 60%);
  pointer-events: none;
}

.hero__noise {
  position: absolute;
  inset: 0;
  background-image: url("data:image/svg+xml,%3Csvg viewBox='0 0 200 200' xmlns='http://www.w3.org/2000/svg'%3E%3Cfilter id='n'%3E%3CfeTurbulence type='fractalNoise' baseFrequency='0.9' numOctaves='4' stitchTiles='stitch'/%3E%3C/filter%3E%3Crect width='100%25' height='100%25' filter='url(%23n)' opacity='0.03'/%3E%3C/svg%3E");
  background-size: 200px 200px;
  opacity: 0.4;
  pointer-events: none;
}

.hero__tag {
  display: inline-block;
  font-size: 0.75rem;
  font-weight: 600;
  letter-spacing: 0.18em;
  text-transform: uppercase;
  color: var(--pink);
  background: rgba(255,45,120,0.1);
  border: 1px solid rgba(255,45,120,0.3);
  border-radius: 999px;
  padding: 0.4rem 1.1rem;
  margin-bottom: 1.8rem;
  animation: fadeUp 0.8s ease both;
}

.hero__title {
  font-family: var(--font-display);
  font-size: clamp(3.5rem, 9vw, 8rem);
  font-weight: 700;
  line-height: 1.0;
  letter-spacing: -0.03em;
  max-width: 800px;
  animation: fadeUp 0.8s 0.1s ease both;
}

.hero__subtitle {
  font-size: 1.25rem;
  color: var(--text-muted);
  margin-top: 1.2rem;
  max-width: 480px;
  animation: fadeUp 0.8s 0.2s ease both;
}

.hero__quote {
  position: relative;
  margin-top: 3rem;
  max-width: 680px;
  padding: 2rem 2.5rem;
  background: rgba(255,45,120,0.06);
  border: 1px solid rgba(255,45,120,0.25);
  border-left: 4px solid var(--pink);
  border-radius: var(--radius);
  animation: fadeUp 0.8s 0.35s ease both;
}

.hero__quote p {
  font-family: var(--font-display);
  font-style: italic;
  font-size: clamp(1.1rem, 2.5vw, 1.45rem);
  line-height: 1.5;
  color: var(--white);
}

.quote__mark {
  font-family: var(--font-display);
  font-size: 4rem;
  line-height: 0;
  color: var(--pink);
  opacity: 0.6;
  position: absolute;
}

.quote__mark { top: 1rem; left: 1rem; }
.quote__mark--close { bottom: -0.5rem; right: 1rem; }

.hero__quote-cite {
  display: block;
  margin-top: 1rem;
  font-size: 0.85rem;
  font-style: normal;
  font-weight: 600;
  letter-spacing: 0.08em;
  color: var(--pink-light);
}

.hero__scroll {
  position: absolute;
  bottom: 2.5rem;
  left: 50%;
  transform: translateX(-50%);
  display: flex;
  flex-direction: column;
  align-items: center;
  gap: 0.5rem;
  font-size: 0.7rem;
  letter-spacing: 0.15em;
  text-transform: uppercase;
  color: var(--text-muted);
  animation: fadeIn 1.5s 0.8s ease both;
}

.scroll__line {
  width: 1px;
  height: 50px;
  background: linear-gradient(to bottom, var(--pink), transparent);
  animation: scrollPulse 2s infinite;
}

/* ============================================================
   STATS BAND
   ============================================================ */
.stats-band {
  background: var(--pink);
  padding: 2.5rem 3rem;
}

.stats-band__inner {
  max-width: 1100px;
  margin: 0 auto;
  display: flex;
  align-items: center;
  justify-content: space-between;
  flex-wrap: wrap;
  gap: 2rem;
}

.stat {
  display: flex;
  flex-direction: column;
  align-items: center;
  text-align: center;
}

.stat__number {
  font-family: var(--font-display);
  font-size: 2.8rem;
  font-weight: 700;
  color: var(--white);
  line-height: 1;
}

.stat__label {
  font-size: 0.78rem;
  font-weight: 500;
  letter-spacing: 0.04em;
  color: rgba(255,255,255,0.75);
  margin-top: 0.3rem;
  max-width: 160px;
  text-align: center;
}

.stat__divider {
  width: 1px;
  height: 60px;
  background: rgba(255,255,255,0.25);
}

/* ============================================================
   SECTIONS — LAYOUT
   ============================================================ */
.section { padding: 7rem 3rem; }
.section--light {
  background: var(--cream);
  background-image: url("data:image/svg+xml,%3Csvg viewBox='0 0 200 200' xmlns='http://www.w3.org/2000/svg'%3E%3Cfilter id='n'%3E%3CfeTurbulence type='fractalNoise' baseFrequency='0.75' numOctaves='4' stitchTiles='stitch'/%3E%3C/filter%3E%3Crect width='100%25' height='100%25' filter='url(%23n)' opacity='0.04'/%3E%3C/svg%3E");
  color: var(--dark);
}
.section--dark  { background: var(--dark-2); color: var(--white); }
.section--pink  { background: var(--pink-pale); color: var(--dark); }
.section--cream {
  background: var(--cream-2);
  background-image: url("data:image/svg+xml,%3Csvg viewBox='0 0 200 200' xmlns='http://www.w3.org/2000/svg'%3E%3Cfilter id='n'%3E%3CfeTurbulence type='fractalNoise' baseFrequency='0.75' numOctaves='4' stitchTiles='stitch'/%3E%3C/filter%3E%3Crect width='100%25' height='100%25' filter='url(%23n)' opacity='0.05'/%3E%3C/svg%3E");
  color: var(--dark);
  position: relative;
  overflow: hidden;
}

.container {
  max-width: 1100px;
  margin: 0 auto;
}

.section__label {
  font-size: 0.72rem;
  font-weight: 700;
  letter-spacing: 0.2em;
  text-transform: uppercase;
  color: var(--pink);
  margin-bottom: 0.8rem;
}

.section__title {
  font-family: var(--font-display);
  font-size: clamp(2rem, 5vw, 3.5rem);
  font-weight: 700;
  line-height: 1.1;
  letter-spacing: -0.02em;
  margin-bottom: 2.5rem;
}

.section__intro {
  font-size: 1.1rem;
  max-width: 680px;
  margin-bottom: 3rem;
  opacity: 0.8;
}

.section__grid {
  display: grid;
  grid-template-columns: 1fr 380px;
  gap: 3rem;
  align-items: start;
}

.section__text p {
  margin-bottom: 1.2rem;
  font-size: 1.05rem;
  opacity: 0.85;
}

.section__text strong { color: var(--pink-deep); font-weight: 600; }

/* ============================================================
   INFO CARD
   ============================================================ */
.info-card {
  border-radius: var(--radius-lg);
  padding: 2rem;
}

.info-card--pink {
  background: linear-gradient(135deg, var(--pink), var(--pink-deep));
  color: var(--white);
}

.info-card__icon {
  font-size: 2.5rem;
  margin-bottom: 1rem;
}

.info-card h3 {
  font-family: var(--font-display);
  font-size: 1.4rem;
  margin-bottom: 1rem;
}

.info-card li {
  padding: 0.5rem 0;
  border-bottom: 1px solid rgba(255,255,255,0.2);
  font-size: 0.95rem;
  font-weight: 500;
}

.info-card li:last-child { border-bottom: none; }

/* ============================================================
   GENE VISUAL
   ============================================================ */
.gene-visual {
  background: var(--dark-3);
  border: 1px solid var(--border);
  border-radius: var(--radius-lg);
  padding: 2.5rem;
  margin-bottom: 3.5rem;
}

.gene-visual__label {
  font-size: 0.75rem;
  font-weight: 700;
  letter-spacing: 0.15em;
  text-transform: uppercase;
  color: var(--pink);
  margin-bottom: 1rem;
}

.gene-visual__bar {
  display: flex;
  align-items: center;
  gap: 1rem;
  flex-wrap: wrap;
}

.gene-visual__segment--normal {
  background: rgba(255,45,120,0.15);
  border: 1px solid rgba(255,45,120,0.4);
  border-radius: 8px;
  padding: 0.6rem 1.2rem;
  font-size: 0.85rem;
  font-weight: 600;
  color: var(--pink-light);
  white-space: nowrap;
}

.gene-visual__gaa {
  display: flex;
  align-items: center;
  gap: 0.4rem;
  flex-wrap: wrap;
}

.gene-visual__gaa span {
  background: var(--pink);
  color: var(--white);
  border-radius: 6px;
  padding: 0.35rem 0.65rem;
  font-size: 0.75rem;
  font-weight: 700;
  letter-spacing: 0.05em;
  animation: pulse 2s infinite;
}

.gene-visual__gaa span:nth-child(2) { animation-delay: 0.1s; }
.gene-visual__gaa span:nth-child(3) { animation-delay: 0.2s; }
.gene-visual__gaa span:nth-child(4) { animation-delay: 0.3s; }
.gene-visual__gaa span:nth-child(5) { animation-delay: 0.4s; }

.gaa--more {
  background: var(--pink-deep) !important;
  font-size: 0.8rem !important;
  padding: 0.35rem 0.8rem !important;
}

.gene-visual__caption {
  margin-top: 1.2rem;
  font-size: 0.82rem;
  color: var(--text-muted);
}

/* ============================================================
   CARDS ROW
   ============================================================ */
.cards-row {
  display: grid;
  grid-template-columns: repeat(3, 1fr);
  gap: 1.5rem;
  margin-bottom: 3rem;
}

.card {
  background: var(--dark-3);
  border: 1px solid var(--border);
  border-radius: var(--radius-lg);
  padding: 2rem;
  transition: transform var(--transition), border-color var(--transition);
}

.card:hover {
  transform: translateY(-4px);
  border-color: rgba(255,45,120,0.3);
}

.card__number {
  font-size: 0.72rem;
  font-weight: 700;
  letter-spacing: 0.2em;
  color: var(--pink);
  margin-bottom: 0.8rem;
}

.card h3 {
  font-size: 1.15rem;
  font-weight: 700;
  margin-bottom: 0.8rem;
}

.card p { font-size: 0.92rem; color: var(--text-muted); line-height: 1.65; }
.card strong { color: var(--pink-light); }

/* ============================================================
   PATHWAY
   ============================================================ */
.pathway-visual {
  display: flex;
  align-items: center;
  justify-content: center;
  flex-wrap: wrap;
  gap: 0.5rem;
  background: var(--dark-3);
  border: 1px solid var(--border);
  border-radius: var(--radius-lg);
  padding: 2rem;
}

.pathway__step {
  display: flex;
  flex-direction: column;
  align-items: center;
  text-align: center;
  gap: 0.5rem;
  padding: 1rem 1.2rem;
  border-radius: var(--radius);
  background: rgba(255,255,255,0.03);
  min-width: 120px;
}

.pathway__step--end {
  background: rgba(255,45,120,0.12);
  border: 1px solid rgba(255,45,120,0.3);
}

.pathway__icon { font-size: 1.8rem; }

.pathway__text {
  font-size: 0.82rem;
  font-weight: 600;
  line-height: 1.4;
}

.pathway__text small { font-weight: 400; color: var(--text-muted); display: block; }

.pathway__arrow {
  font-size: 1.4rem;
  color: var(--pink);
  opacity: 0.7;
}

/* ============================================================
   SYMPTOM GRID
   ============================================================ */
.symptom-grid {
  display: grid;
  grid-template-columns: repeat(2, 1fr);
  gap: 1.5rem;
  margin-bottom: 3.5rem;
}

.symptom-category {
  background: var(--white);
  border-radius: var(--radius-lg);
  padding: 2rem;
  box-shadow: 0 4px 24px rgba(0,0,0,0.06);
  transition: transform var(--transition);
}

.symptom-category:hover { transform: translateY(-3px); }

.symptom-category__header {
  display: flex;
  align-items: center;
  gap: 0.8rem;
  margin-bottom: 1.2rem;
}

.symptom-category__icon { font-size: 1.6rem; }

.symptom-category h3 {
  font-size: 1.05rem;
  font-weight: 700;
  color: var(--dark);
}

.symptom-list li {
  display: flex;
  align-items: center;
  gap: 0.7rem;
  padding: 0.45rem 0;
  border-bottom: 1px solid var(--pink-pale);
  font-size: 0.9rem;
  color: #333;
}

.symptom-list li:last-child { border-bottom: none; }

.symptom-dot {
  width: 7px; height: 7px;
  border-radius: 50%;
  background: var(--pink);
  flex-shrink: 0;
}

/* ============================================================
   TIMELINE
   ============================================================ */
.timeline {
  background: var(--white);
  border-radius: var(--radius-lg);
  padding: 2.5rem;
  box-shadow: 0 4px 24px rgba(0,0,0,0.06);
}

.timeline__title {
  font-family: var(--font-display);
  font-size: 1.3rem;
  color: var(--dark);
  margin-bottom: 2rem;
}

.timeline__track {
  display: flex;
  gap: 0;
  position: relative;
}

.timeline__track::before {
  content: '';
  position: absolute;
  top: 12px;
  left: 12px;
  right: 12px;
  height: 2px;
  background: linear-gradient(to right, var(--pink), var(--pink-light));
}

.timeline__item {
  flex: 1;
  display: flex;
  flex-direction: column;
  align-items: center;
  text-align: center;
  padding-top: 0.5rem;
  gap: 1rem;
}

.timeline__dot {
  width: 24px; height: 24px;
  border-radius: 50%;
  background: var(--pink);
  border: 4px solid var(--white);
  box-shadow: 0 0 0 2px var(--pink);
  position: relative;
  z-index: 1;
  flex-shrink: 0;
}

.timeline__content {
  padding-top: 0.5rem;
}

.timeline__content strong {
  display: block;
  font-weight: 700;
  color: var(--pink-deep);
  margin-bottom: 0.3rem;
  font-size: 0.95rem;
}

.timeline__content p {
  font-size: 0.82rem;
  color: #555;
  max-width: 180px;
}

/* ============================================================
   THERAPY SECTION
   ============================================================ */
.therapy-hero {
  background: linear-gradient(135deg, var(--pink), var(--pink-deep));
  border-radius: var(--radius-lg);
  padding: 3rem;
  color: var(--white);
  margin-bottom: 3rem;
  position: relative;
  overflow: hidden;
}

.therapy-hero::before {
  content: '';
  position: absolute;
  top: -60px; right: -60px;
  width: 300px; height: 300px;
  border-radius: 50%;
  background: rgba(255,255,255,0.06);
}

.therapy-hero__badge {
  display: inline-block;
  background: rgba(255,255,255,0.2);
  border-radius: 999px;
  padding: 0.35rem 1rem;
  font-size: 0.75rem;
  font-weight: 700;
  letter-spacing: 0.1em;
  text-transform: uppercase;
  margin-bottom: 1rem;
}

.therapy-hero__name {
  font-family: var(--font-display);
  font-size: 3rem;
  font-weight: 700;
  line-height: 1;
  margin-bottom: 0.3rem;
}

.therapy-hero__brand {
  font-size: 0.9rem;
  opacity: 0.75;
  margin-bottom: 1.5rem;
}

.therapy-hero__desc {
  font-size: 1.05rem;
  max-width: 600px;
  line-height: 1.7;
  opacity: 0.95;
  margin-bottom: 2rem;
}

.therapy-hero__desc strong { font-weight: 700; }

.therapy-hero__facts {
  display: flex;
  gap: 2.5rem;
  flex-wrap: wrap;
}

.therapy-fact {
  display: flex;
  flex-direction: column;
}

.therapy-fact strong {
  font-size: 2rem;
  font-weight: 700;
  font-family: var(--font-display);
  line-height: 1;
}

.therapy-fact span {
  font-size: 0.8rem;
  opacity: 0.75;
  margin-top: 0.2rem;
}

.subsection__title {
  font-family: var(--font-display);
  font-size: 1.6rem;
  font-weight: 700;
  color: var(--dark);
  margin-bottom: 1.5rem;
}

.support-grid {
  display: grid;
  grid-template-columns: repeat(3, 1fr);
  gap: 1.2rem;
}

.support-card {
  background: var(--white);
  border-radius: var(--radius);
  padding: 1.5rem;
  box-shadow: 0 2px 16px rgba(0,0,0,0.06);
  transition: transform var(--transition), box-shadow var(--transition);
}

.support-card:hover {
  transform: translateY(-3px);
  box-shadow: 0 8px 30px rgba(255,45,120,0.12);
}

.support-card__icon { font-size: 1.8rem; margin-bottom: 0.8rem; display: block; }

.support-card h4 {
  font-size: 1rem;
  font-weight: 700;
  color: var(--dark);
  margin-bottom: 0.5rem;
}

.support-card p { font-size: 0.85rem; color: #555; line-height: 1.6; }

/* ============================================================
   RESEARCH CARDS
   ============================================================ */
.research-cards {
  display: grid;
  grid-template-columns: repeat(3, 1fr);
  gap: 1.5rem;
  margin-bottom: 3rem;
}

.research-card {
  background: var(--dark-3);
  border: 1px solid var(--border);
  border-radius: var(--radius-lg);
  padding: 2rem;
  position: relative;
  transition: border-color var(--transition), transform var(--transition);
}

.research-card:hover {
  border-color: rgba(255,45,120,0.4);
  transform: translateY(-4px);
}

.research-card__phase {
  display: inline-block;
  background: rgba(255,45,120,0.12);
  color: var(--pink-light);
  border: 1px solid rgba(255,45,120,0.25);
  border-radius: 999px;
  padding: 0.25rem 0.85rem;
  font-size: 0.7rem;
  font-weight: 700;
  letter-spacing: 0.1em;
  text-transform: uppercase;
  margin-bottom: 1rem;
}

.research-card h3 {
  font-family: var(--font-display);
  font-size: 1.5rem;
  margin-bottom: 0.8rem;
}

.research-card p {
  font-size: 0.9rem;
  color: var(--text-muted);
  line-height: 1.65;
  margin-bottom: 1.2rem;
}

.research-card__tag {
  display: inline-block;
  background: var(--dark);
  border: 1px solid var(--border);
  border-radius: 8px;
  padding: 0.3rem 0.8rem;
  font-size: 0.75rem;
  font-weight: 600;
  color: var(--white);
}

.hope-banner {
  background: linear-gradient(135deg, rgba(255,45,120,0.12), rgba(196,0,90,0.08));
  border: 1px solid rgba(255,45,120,0.25);
  border-radius: var(--radius-lg);
  padding: 2.5rem 3rem;
  text-align: center;
}

.hope-banner p {
  font-family: var(--font-display);
  font-style: italic;
  font-size: 1.2rem;
  color: var(--pink-light);
  max-width: 680px;
  margin: 0 auto;
  line-height: 1.6;
}

/* ============================================================
   DEDICATION
   ============================================================ */
.dedication {
  background: var(--dark);
  padding: 8rem 3rem;
  text-align: center;
  position: relative;
  overflow: hidden;
}

.dedication::before {
  content: '';
  position: absolute;
  inset: 0;
  background: radial-gradient(ellipse 70% 60% at 50% 50%, rgba(255,45,120,0.15) 0%, transparent 70%);
  pointer-events: none;
}

.dedication__inner {
  position: relative;
  z-index: 1;
  max-width: 640px;
  margin: 0 auto;
}

.dedication__heart {
  font-size: 4rem;
  color: var(--pink);
  display: block;
  margin-bottom: 1.5rem;
  animation: heartbeat 2.2s ease infinite;
}

.dedication__text {
  font-size: 1.2rem;
  color: var(--text-muted);
  line-height: 1.8;
  margin-bottom: 2rem;
}

.dedication__line {
  width: 60px;
  height: 2px;
  background: var(--pink);
  margin: 0 auto 2rem;
  border-radius: 2px;
}

.dedication__quote {
  font-family: var(--font-display);
  font-style: italic;
  font-size: 1.35rem;
  color: var(--white);
  line-height: 1.6;
  margin-bottom: 1.5rem;
}

.dedication__cite {
  display: block;
  font-size: 0.9rem;
  font-style: normal;
  font-weight: 600;
  letter-spacing: 0.1em;
  color: var(--pink);
  margin-top: 0.8rem;
}

.dedication__sub {
  font-size: 1rem;
  color: var(--pink-light);
  margin-top: 1.2rem;
}

/* ============================================================
   FOOTER
   ============================================================ */
.footer {
  background: var(--dark-3);
  border-top: 1px solid var(--border);
  padding: 2.5rem 3rem;
}

.footer__inner {
  max-width: 1100px;
  margin: 0 auto;
  display: flex;
  flex-direction: column;
  align-items: center;
  text-align: center;
  gap: 0.8rem;
}

.footer p { font-size: 0.88rem; color: var(--text-muted); }

.footer__sources {
  font-size: 0.75rem !important;
  opacity: 0.5;
}

/* ============================================================
   ANIMATIONS
   ============================================================ */
@keyframes fadeUp {
  from { opacity: 0; transform: translateY(28px); }
  to   { opacity: 1; transform: translateY(0); }
}

@keyframes fadeIn {
  from { opacity: 0; }
  to   { opacity: 1; }
}

@keyframes pulse {
  0%, 100% { transform: scale(1); }
  50%       { transform: scale(1.06); }
}

@keyframes scrollPulse {
  0%, 100% { opacity: 0.4; transform: scaleY(1); }
  50%       { opacity: 1;   transform: scaleY(1.15); }
}

@keyframes heartbeat {
  0%, 100% { transform: scale(1); }
  14%       { transform: scale(1.15); }
  28%       { transform: scale(1); }
  42%       { transform: scale(1.1); }
  70%       { transform: scale(1); }
}

/* ============================================================
   SCROLL REVEAL
   ============================================================ */
.reveal {
  opacity: 0;
  transform: translateY(32px);
  transition: opacity 0.7s ease, transform 0.7s ease;
}

.reveal.visible {
  opacity: 1;
  transform: translateY(0);
}

/* ============================================================
   SVG ICON SYSTEM
   ============================================================ */
.icon-svg {
  display: block;
  flex-shrink: 0;
}
.info-card__icon .icon-svg   { width: 46px; height: 46px; color: rgba(255,255,255,0.95); }
.symptom-category__icon      { display: flex; align-items: center; }
.symptom-category__icon .icon-svg { width: 28px; height: 28px; color: var(--pink); }
.support-card__icon          { display: flex; align-items: center; margin-bottom: 0.8rem; }
.support-card__icon .icon-svg { width: 32px; height: 32px; color: var(--pink); }
.pathway__icon               { display: flex; align-items: center; justify-content: center; }
.pathway__icon .icon-svg     { width: 34px; height: 34px; color: var(--pink-light); }
.pathway__step--end .pathway__icon .icon-svg { color: white; }

/* ============================================================
   PILL LABELS (from Yasmin's Präsentation style)
   ============================================================ */
.pill-label {
  display: inline-block;
  background: var(--pink);
  color: var(--white);
  border-radius: 999px;
  padding: 0.35rem 1.1rem;
  font-size: 0.85rem;
  font-weight: 800;
  letter-spacing: 0.02em;
  margin-bottom: 1.2rem;
}

/* ============================================================
   DECORATIVE ELEMENTS — Scrapbook-Ästhetik
   ============================================================ */

/* Spiky Burst (schwarze Sternform aus der Präsentation) */
.deco-burst {
  position: absolute;
  width: 90px;
  height: 90px;
  pointer-events: none;
  z-index: 0;
}
.deco-burst svg { width: 100%; height: 100%; }
.deco-burst--tl { top: -20px; left: -20px; }
.deco-burst--tr { top: -20px; right: -20px; transform: rotate(20deg); }
.deco-burst--bl { bottom: -20px; left: -20px; transform: rotate(-15deg); }
.deco-burst--br { bottom: -20px; right: -20px; transform: rotate(30deg); }
.deco-burst--sm { width: 55px; height: 55px; }
.deco-burst--lg { width: 130px; height: 130px; }

/* Loop / Federspule-Doodle */
.deco-loop {
  position: absolute;
  opacity: 0.35;
  pointer-events: none;
  z-index: 0;
}
.deco-loop--l  { left: -10px; top: 50%; transform: translateY(-50%); }
.deco-loop--r  { right: -10px; top: 50%; transform: translateY(-50%); }
.deco-loop--bl { bottom: 20px; left: 20px; }
.deco-loop--br { bottom: 20px; right: 20px; }

/* Punkt-Raster */
.deco-dots {
  position: absolute;
  width: 80px;
  height: 80px;
  background-image: radial-gradient(circle, var(--pink) 1.5px, transparent 1.5px);
  background-size: 10px 10px;
  opacity: 0.35;
  pointer-events: none;
  z-index: 0;
  border-radius: 4px;
}
.deco-dots--tr { top: 30px; right: 50px; }
.deco-dots--bl { bottom: 30px; left: 50px; }
.deco-dots--tl { top: 30px; left: 80px; }

/* Stern (grau, wie in Präsentation) */
.deco-star-shape {
  position: absolute;
  pointer-events: none;
  z-index: 0;
  opacity: 0.65;
}
.deco-star-shape svg { width: 100%; height: 100%; }
.deco-star-shape--sm { width: 40px; height: 40px; }
.deco-star-shape--md { width: 65px; height: 65px; }

/* Pink Tape-Streifen */
.deco-tape {
  position: absolute;
  background: rgba(255, 45, 120, 0.18);
  height: 28px;
  width: 120px;
  transform: rotate(-8deg);
  pointer-events: none;
  z-index: 0;
  border-radius: 2px;
}
.deco-tape--tr { top: 20px; right: 60px; transform: rotate(12deg); }

/* ============================================================
   YASMIN SECTION
   ============================================================ */
.yasmin-section {
  background: var(--cream);
  background-image: url("data:image/svg+xml,%3Csvg viewBox='0 0 200 200' xmlns='http://www.w3.org/2000/svg'%3E%3Cfilter id='n'%3E%3CfeTurbulence type='fractalNoise' baseFrequency='0.75' numOctaves='4' stitchTiles='stitch'/%3E%3C/filter%3E%3Crect width='100%25' height='100%25' filter='url(%23n)' opacity='0.055'/%3E%3C/svg%3E");
  padding: 7rem 3rem;
  position: relative;
  overflow: hidden;
  color: var(--dark);
}

.yasmin-grid {
  display: grid;
  grid-template-columns: 1fr 360px;
  gap: 4rem;
  align-items: center;
  position: relative;
  z-index: 1;
}

.yasmin-main-quote {
  position: relative;
  margin-bottom: 2.5rem;
}

.yasmin-main-quote blockquote {
  font-family: var(--font-display);
  font-style: italic;
  font-size: clamp(1.5rem, 3.5vw, 2.2rem);
  line-height: 1.35;
  color: var(--dark);
  font-weight: 700;
  margin-bottom: 0.6rem;
}

.yasmin-main-quote cite {
  font-size: 0.9rem;
  font-weight: 600;
  color: var(--pink-deep);
  font-style: normal;
  letter-spacing: 0.04em;
}

.yasmin-quote-bar {
  width: 5px;
  height: 100%;
  background: var(--pink);
  position: absolute;
  left: -1.5rem;
  top: 0;
  border-radius: 4px;
}

.yasmin-facts {
  list-style: none;
  display: flex;
  flex-direction: column;
  gap: 0.7rem;
}

.yasmin-facts li {
  display: flex;
  align-items: center;
  gap: 0.8rem;
  font-size: 0.97rem;
  font-weight: 500;
  color: #333;
}

.star-bullet {
  color: var(--pink);
  font-size: 1rem;
  flex-shrink: 0;
}

/* Stamp / Polaroid Frame (Stil aus Präsentation) */
.stamp-wrap {
  display: flex;
  flex-direction: column;
  align-items: center;
  gap: 1rem;
}

.stamp-frame {
  position: relative;
  padding: 16px;
  background: var(--pink-pale);
  border-radius: 4px;
  /* scalloped border via mask */
  --s: 18px;
  mask:
    radial-gradient(var(--s) at 0 0, #0000 98%, #000) 0 0,
    radial-gradient(var(--s) at 100% 0, #0000 98%, #000) 100% 0,
    radial-gradient(var(--s) at 0 100%, #0000 98%, #000) 0 100%,
    radial-gradient(var(--s) at 100% 100%, #0000 98%, #000) 100% 100%,
    radial-gradient(var(--s) at 0 50%, #0000 98%, #000) 0,
    radial-gradient(var(--s) at 100% 50%, #0000 98%, #000) 100%,
    radial-gradient(var(--s) at 50% 0, #0000 98%, #000) 0,
    radial-gradient(var(--s) at 50% 100%, #0000 98%, #000) 0 100%,
    linear-gradient(#000 0 0) center / calc(100% - var(--s)) calc(100% - var(--s)) no-repeat,
    linear-gradient(#000 0 0) center / calc(100% - 0px) calc(100% - var(--s)*2) no-repeat,
    linear-gradient(#000 0 0) center / calc(100% - var(--s)*2) calc(100% - 0px) no-repeat;
  mask-repeat: no-repeat;
  transform: rotate(-2deg);
  box-shadow: 4px 6px 20px rgba(0,0,0,0.12);
  width: 280px;
}

.stamp-inner {
  background: var(--cream-2);
  border-radius: 2px;
  width: 100%;
  aspect-ratio: 4/3;
  display: flex;
  align-items: center;
  justify-content: center;
  position: relative;
  overflow: hidden;
}

.stamp-photo {
  width: 100%;
  height: 100%;
  object-fit: cover;
  object-position: center top;
  display: block;
  border-radius: 2px;
}

.stamp-name-tag {
  background: #3D3D3D;
  color: var(--white);
  border-radius: 999px;
  padding: 0.45rem 1.4rem;
  font-size: 0.95rem;
  font-weight: 600;
  font-family: var(--font-display);
  font-style: italic;
  letter-spacing: 0.03em;
  box-shadow: 2px 3px 10px rgba(0,0,0,0.2);
}

/* ============================================================
   HERO — Deko-Elemente
   ============================================================ */
.hero__decos {
  position: absolute;
  inset: 0;
  pointer-events: none;
  overflow: hidden;
}

/* ============================================================
   HAMBURGER BUTTON
   ============================================================ */
.nav__burger {
  display: none;
  flex-direction: column;
  justify-content: center;
  gap: 5px;
  background: none;
  border: none;
  cursor: pointer;
  padding: 6px;
  z-index: 101;
  flex-shrink: 0;
}
.nav__burger span {
  display: block;
  width: 22px;
  height: 2px;
  background: var(--white);
  border-radius: 2px;
  transition: transform 0.3s ease, opacity 0.3s ease;
  transform-origin: center;
}
.nav--open .nav__burger span:nth-child(1) { transform: translateY(7px) rotate(45deg); }
.nav--open .nav__burger span:nth-child(2) { opacity: 0; transform: scaleX(0); }
.nav--open .nav__burger span:nth-child(3) { transform: translateY(-7px) rotate(-45deg); }

/* ============================================================
   RESPONSIVE — TABLET (≤ 900px)
   ============================================================ */
@media (max-width: 900px) {
  html, body { overflow-x: hidden; }

  .nav { padding: 1rem 1.5rem; }
  .nav__links { gap: 1.2rem; }
  .nav__links a { font-size: 0.78rem; }

  .hero { padding: 8rem 1.5rem 4rem; }
  .hero__decos .deco-burst--lg { width: 80px; height: 80px; }

  .section { padding: 5rem 1.5rem; }
  .yasmin-section { padding: 5rem 1.5rem; }

  .section__grid { grid-template-columns: 1fr; }
  .cards-row { grid-template-columns: 1fr; }
  .symptom-grid { grid-template-columns: 1fr; }
  .support-grid { grid-template-columns: repeat(2, 1fr); }
  .research-cards { grid-template-columns: 1fr; }

  .yasmin-grid { grid-template-columns: 1fr; gap: 2.5rem; }
  .stamp-wrap { align-items: flex-start; }
  .stamp-frame { width: 240px; }

  .stats-band { padding: 2rem 1.5rem; }
  .stats-band__inner { flex-wrap: wrap; justify-content: center; gap: 1.5rem 3rem; }
  .stat__divider { display: none; }

  .pathway-visual { flex-direction: column; align-items: stretch; }
  .pathway__arrow { transform: rotate(90deg); text-align: center; }
  .pathway__step { width: 100%; }

  .timeline__track { flex-direction: column; align-items: flex-start; gap: 1.5rem; }
  .timeline__track::before { top: 12px; left: 12px; bottom: 12px; right: auto; width: 2px; height: auto; }
  .timeline__item { flex-direction: row; text-align: left; }
  .timeline__content { padding-top: 0; }
  .timeline__content p { max-width: 100%; }

  .therapy-hero__facts { flex-wrap: wrap; gap: 1.5rem; }

  .deco-loop--r { display: none; }
}

/* ============================================================
   RESPONSIVE — MOBILE (≤ 600px)
   ============================================================ */
@media (max-width: 600px) {
  /* --- Nav & Hamburger --- */
  .nav { padding: 1rem 1.2rem; }
  .nav__burger { display: flex; }
  .nav__links { display: none; }

  /* Nav wird selbst zum Fullscreen-Overlay — vermeidet backdrop-filter z-index Bug */
  .nav--open {
    bottom: 0;
    flex-direction: column;
    align-items: center;
    justify-content: center;
    background: rgba(13,13,13,0.98);
    border-bottom: none;
    z-index: 200;
  }
  .nav--open .nav__logo { position: absolute; top: 1.2rem; left: 1.2rem; }
  .nav--open .nav__burger { position: absolute; top: 1rem; right: 1.2rem; }
  .nav--open .nav__links {
    display: flex;
    flex-direction: column;
    align-items: center;
    gap: 2.2rem;
  }
  .nav--open .nav__links a {
    font-size: 1.3rem;
    font-weight: 600;
    letter-spacing: 0.08em;
    color: var(--white);
  }
  .nav--open .nav__links a:hover { color: var(--pink); }

  /* --- Hero --- */
  .hero { padding: 6.5rem 1.2rem 3rem; }
  .hero__title { font-size: 2.4rem; letter-spacing: -0.02em; }
  .hero__subtitle { font-size: 1rem; }
  .hero__tag { font-size: 0.65rem; padding: 0.35rem 0.9rem; }
  .hero__quote { padding: 1.4rem 1.2rem 1.4rem 1.4rem; margin-top: 2rem; }
  .hero__quote p { font-size: 1rem; }
  .quote__mark { font-size: 2.2rem; top: 0.5rem; left: 0.5rem; }
  .quote__mark--close { bottom: -0.3rem; right: 0.5rem; }
  .hero__decos { display: none; }
  .hero__scroll { display: none; }

  /* --- Sections --- */
  .section { padding: 3.5rem 1.2rem; }
  .yasmin-section { padding: 3.5rem 1.2rem; }
  .section__title { font-size: 2rem; margin-bottom: 1.2rem; }

  /* --- Stats band --- */
  .stats-band { padding: 2rem 1.2rem; }
  .stats-band__inner { flex-direction: column; align-items: center; gap: 1.5rem; }
  .stat__number { font-size: 2.2rem; }

  /* --- Yasmin --- */
  .yasmin-grid { grid-template-columns: 1fr; gap: 2rem; }
  .stamp-wrap { align-items: center; }
  .stamp-frame { width: 200px; transform: rotate(-1.5deg); }
  .yasmin-quote-bar { display: none; }
  .yasmin-main-quote { padding-left: 0; }
  .yasmin-main-quote blockquote { font-size: 1.2rem; }
  .yasmin-facts li { font-size: 0.9rem; }

  /* --- Gene Visual --- */
  .gene-visual { padding: 1.4rem; }
  .gene-visual__bar { flex-direction: column; align-items: flex-start; gap: 0.8rem; }
  .gene-visual__gaa { flex-wrap: wrap; gap: 0.3rem; }

  /* --- Pathway --- */
  .pathway-visual { padding: 1.2rem; gap: 0.3rem; }
  .pathway__step { padding: 0.8rem 1rem; }
  .pathway__text { font-size: 0.78rem; }
  .pathway__icon .icon-svg { width: 26px; height: 26px; }

  /* --- Symptome --- */
  .symptom-category { padding: 1.4rem; }
  .symptom-list li { font-size: 0.85rem; }

  /* --- Timeline --- */
  .timeline { padding: 1.5rem; }

  /* --- Therapie --- */
  .therapy-hero { padding: 1.8rem 1.4rem; }
  .therapy-hero__name { font-size: 1.9rem; }
  .therapy-hero__desc { font-size: 0.92rem; }
  .therapy-hero__facts { flex-direction: column; gap: 1rem; }
  .therapy-fact strong { font-size: 1.6rem; }
  .support-grid { grid-template-columns: 1fr; }
  .support-card { padding: 1.2rem; }

  /* --- Forschung --- */
  .hope-banner { padding: 2rem 1.4rem; }
  .hope-banner p { font-size: 1rem; }

  /* --- Dedication --- */
  .dedication { padding: 5rem 1.4rem; }
  .dedication__heart { font-size: 3rem; }
  .dedication__quote { font-size: 1.05rem; }
  .dedication__text { font-size: 1rem; }

  /* --- Cards allgemein --- */
  .card { padding: 1.5rem; }
  .info-card { padding: 1.5rem; }
  .research-card { padding: 1.5rem; }

  /* --- Deko-Elemente ausblenden damit kein horizontaler Scroll --- */
  .deco-burst, .deco-loop, .deco-tape, .deco-dots, .deco-star-shape { display: none; }
}